Issue 1, 2006

Biochemistry of human skin—our brain on the outside

Abstract

The skin, our body's largest organ, is located at the interface between the external and internal environments, and so is strategically placed to provide not only a barrier against a range of noxious stressors (UV radiation, mechanical, chemical and biological insults) but also to act as the periphery's ‘sensing’ system. Recent developments suggest that this organ is much more critical to maintaining body homeostasis than previously thought. This tutorial review introduces the reader to some of the biochemistry that underpins the skin's enormous multi-functionality.

Graphical abstract: Biochemistry of human skin—our brain on the outside

Article information

Article type
Tutorial Review
Submitted
27 Aug 2005
First published
26 Oct 2005

Chem. Soc. Rev., 2006,35, 52-67

Biochemistry of human skin—our brain on the outside

D. J. Tobin, Chem. Soc. Rev., 2006, 35, 52 DOI: 10.1039/B505793K

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