Issue 2, 2011
From the journal:

Organic & Biomolecular Chemistry

Wilsoniamines A and B: novel alkaloids from the temperate Australian bryozoan, Amathia wilsoni†

Anthony R. Carroll,*ab   Sandra Duffy,b   Melissa Sykesb  and  Vicky M. Averyb  

* Corresponding authors

a Environmental Futures Centre, Griffith University, Gold Coast, Australia
E-mail: a.carroll@griffith.edu.au
Fax: +61 7 5527785
Tel: +61 7 5552918

b Eskitis Institute, Griffith University, Brisbane, Australia

Abstract

Two novel alkaloids, wilsoniamines A and B, both possessing a hexahydropyrrolo[1,2-c]imidazol-1-one ring system that has not previously been found in nature, together with a new alkaloid, amathamide H and a known alkaloid, amathamide C were isolated from the temperate Australian bryozoan, Amathia wilsoni. MS and NMR analysis established the structure of the new compounds and indicated that the structure of amathamide C and several related compounds be revised. Amathamides C and H showed moderate anti-malarial and anti-trypanosomal activity.

Graphical abstract: Wilsoniamines A and B: novel alkaloids from the temperate Australian bryozoan, Amathia wilsoni

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Article information

DOI
https://doi.org/10.1039/C0OB00538J
Article type
Paper
Submitted
04 Aug 2010
Accepted
23 Sep 2010
First published
24 Sep 2010

Org. Biomol. Chem., 2011,9, 604-609

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Wilsoniamines A and B: novel alkaloids from the temperate Australian bryozoan, Amathia wilsoni

A. R. Carroll, S. Duffy, M. Sykes and V. M. Avery, Org. Biomol. Chem., 2011, 9, 604 DOI: 10.1039/C0OB00538J

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