Issue 1, 2013

Continuum- and particle-based modeling of shapes and dynamics of red blood cells in health and disease

Abstract

We review recent advances in multiscale modeling of the mechanics of healthy and diseased red blood cells (RBCs), and blood flow in the microcirculation. We cover the traditional continuum-based methods but also particle-based methods used to model both the RBCs and the blood plasma. We highlight examples of successful simulations of blood flow including malaria and sickle cell anemia.

Graphical abstract: Continuum- and particle-based modeling of shapes and dynamics of red blood cells in health and disease

Article information

Article type
Tutorial Review
Submitted
14 Aug 2012
Accepted
04 Oct 2012
First published
22 Oct 2012

Soft Matter, 2013,9, 28-37

Continuum- and particle-based modeling of shapes and dynamics of red blood cells in health and disease

X. Li, P. M. Vlahovska and G. E. Karniadakis, Soft Matter, 2013, 9, 28 DOI: 10.1039/C2SM26891D

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