Issue 71, 2014
From the journal:

Chemical Communications

Towards intelligent bioreactor systems: triggering the release and mixing of compounds based on DNA-functionalized hybrid hydrogel†

Li Zhou,‡ab   Cuie Chen,‡ab   Jinsong Ren*a  and  Xiaogang Qu*a  

* Corresponding authors

a State Key Laboratory of Rare Earth Resource Utilization and Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China
E-mail: jren@ciac.ac.cn, xqu@ciac.ac.cn

b Graduate School of the Chinese Academy of Sciences, Beijing 100039, P. R. China

Abstract

We have designed and synthesized an intelligent mesoporous silica nanoparticle–DNA hydrogel bioreactor system that can be controlled by external stimuli. The system allowed the simultaneous incorporation of multiple components, and the separation between the components can be destroyed by a structural change of the DNA to initiate a reaction.

Graphical abstract: Towards intelligent bioreactor systems: triggering the release and mixing of compounds based on DNA-functionalized hybrid hydrogel

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Article information

DOI
https://doi.org/10.1039/C4CC04791E
Article type
Communication
Submitted
24 Jun 2014
Accepted
13 Jul 2014
First published
14 Jul 2014

Chem. Commun., 2014,50, 10255-10257

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Towards intelligent bioreactor systems: triggering the release and mixing of compounds based on DNA-functionalized hybrid hydrogel

L. Zhou, C. Chen, J. Ren and X. Qu, Chem. Commun., 2014, 50, 10255 DOI: 10.1039/C4CC04791E

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