Issue 20, 2015
From the journal:

RSC Advances

A facile one-pot synthesis of l-DOPA imprinted silica nanospheres for chiral separation and in vitro controlled release†

Chang-Long Kao,a   Yan-Fu Chen,a   Ping-Chih Huang,b   Ching-Yun Hsub  and  Chun-Hsiung Kuei*a  

* Corresponding authors

a Department of Chemistry, National Cheng Kung University, Tainan City 701, Taiwan, Republic of China
E-mail: kuei@mail.ncku.edu.tw
Fax: +886-6-2089092
Tel: +886-6-2089092

b Department of Chemical and Materials Engineering, Cheng Shiu University, Kaohsiung Country 83347, Taiwan, Republic of China

Abstract

A one-pot methodology was successfully developed to synthesize chiral imprinted silica nanospheres with hollow and mesoporous structures. These silica nanospheres demonstrated high capacity and chiral selectivity for L- or D-3,4-dihydroxyphenylalanine (L- or D-DOPA) and possessed potency for L-DOPA controlled release.

Graphical abstract: A facile one-pot synthesis of l-DOPA imprinted silica nanospheres for chiral separation and in vitro controlled release

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Article information

DOI
https://doi.org/10.1039/C4RA16698A
Article type
Communication
Submitted
19 Dec 2014
Accepted
27 Jan 2015
First published
27 Jan 2015

RSC Adv., 2015,5, 15511-15514

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A facile one-pot synthesis of L-DOPA imprinted silica nanospheres for chiral separation and in vitro controlled release

C. Kao, Y. Chen, P. Huang, C. Hsu and C. Kuei, RSC Adv., 2015, 5, 15511 DOI: 10.1039/C4RA16698A

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