Issue 37, 2016
From the journal:

Chemical Communications

Cancer cell-targeted two-photon fluorescence probe for the real-time ratiometric imaging of DNA damage†‡

Hua Zhang,*a   Kui Wang,a   Xiaopeng Xuan,a   Qingzhang Lv,a   Yamin Niea  and  Haiming Guo*a  

* Corresponding authors

a Henan Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Key Laboratory of Green Chemical Media and Reactions, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering Institution, Henan Normal University, 453007 Xinxiang, China
E-mail: zhh1106@htu.edu.cn, zhanghua1106@163.com, ghm@htu.edu.cn

Abstract

Real-time imaging of DNA damage in cancer cells could provide valuable information on the formation and development of cancer. Herein, a two-photon fluorescence probe was discovered. Through sequential ICT processes, it allows successful in vivo visualization of DNA damage in cancer cells by one/two-photon microscopic imaging or by the unaided eye and a hand-held ultraviolet lamp.

Graphical abstract: Cancer cell-targeted two-photon fluorescence probe for the real-time ratiometric imaging of DNA damage

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Article information

DOI
https://doi.org/10.1039/C6CC02290A
Article type
Communication
Submitted
16 Mar 2016
Accepted
07 Apr 2016
First published
07 Apr 2016

Chem. Commun., 2016,52, 6308-6311

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Cancer cell-targeted two-photon fluorescence probe for the real-time ratiometric imaging of DNA damage

H. Zhang, K. Wang, X. Xuan, Q. Lv, Y. Nie and H. Guo, Chem. Commun., 2016, 52, 6308 DOI: 10.1039/C6CC02290A

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