Phosphovanadomolybdic acid catalyzed direct C–H trifluoromethylation of (hetero)arenes using NaSO2CF3 as the CF3 source and O2 as the terminal oxidant†
Kosuke
Suzuki, 
a
Kazuya
Yamaguchi
*a
and
a
Kazuya
Yamaguchi
*a
and
Abstract
A direct C–H trifluoromethylation of (hetero)arenes using NaSO2CF3 (Langlois' reagent) as the CF3 source and O2 as the terminal oxidant has been developed. In the presence of catalytic amounts of phosphovanadomolybdic acids, such as H6PV3Mo9O40, various kinds of substituted benzenes and heteroaromatic compounds could be converted into the corresponding trifluoromethylated products.
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