Issue 95, 2018

A DR4 capturer with AKT siRNA for the synergetic enhancement of death receptor-mediated apoptosis

Abstract

A graphene-based nanocarrier modified with death receptor 4 (DR4) antibody and AKT siRNA has been developed, which can synergistically strengthen death receptor-mediated apoptosis and enhance the cancer therapeutic effect in vivo.

Graphical abstract: A DR4 capturer with AKT siRNA for the synergetic enhancement of death receptor-mediated apoptosis

Supplementary files

Article information

Article type
Communication
Submitted
21 Aug 2018
Accepted
06 Nov 2018
First published
06 Nov 2018

Chem. Commun., 2018,54, 13439-13442

A DR4 capturer with AKT siRNA for the synergetic enhancement of death receptor-mediated apoptosis

W. Pan, S. Gong, Y. Li, H. Zhang, N. Li and B. Tang, Chem. Commun., 2018, 54, 13439 DOI: 10.1039/C8CC06796A

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