5-Formyluracil as a cornerstone for aluminum detection in vitro and in vivo: a more natural and sustainable strategy

Abstract

5-Formyluracil (5fU) based probes were designed and synthesized to detect Al³⁺ ions in vitro and in biological systems. These probes were synthesised using furan-2-carbohydrazide (fr) and 5fU derivatives. We also selectively labelled 5-formyluracil in DNA with the help of Al³⁺.