Issue 4, 2019
From the journal:

Chemical Communications

Two photon excitable graphene quantum dots for structured illumination microscopy and imaging applications: lysosome specificity and tissue-dependent imaging†

Harwinder Singh,‡af   Sreejesh Sreedharan,‡b   Karishma Tiwari,a   Nicola H. Green, ORCID logo cd   Carl Smythe,e   Sumit Kumar Pramanik, ORCID logo *a   Jim A. Thomas ORCID logo *b  and  Amitava Das ORCID logo *a  

* Corresponding authors

a CSIR-Central Salt and Marine Chemicals Research Institute, Bhavnagar, Gujarat, India
E-mail: sumitpramanik007@gmail.com, a.das@csmcri.res.in

b Department of Chemistry, University of Sheffield, Western Bank, Sheffield, UK
E-mail: James.thomas@sheffield.ac.uk

c Department of Materials Science and Engineering, Kroto Research Institute, North Campus, Broad Lane, University of Sheffield, Sheffield, UK

d INSIGNEO Institute for in silico Medicine, Sheffield, UK

e Department of Biomedical Science, University of Sheffield, Sheffield, UK

f Academy of Scientific & Innovative Research, CSIR-CSMCRI, Gujarat, India

Abstract

Biocompatible graphene quantum dots (GQDs), obtained from extracts of neem root, are found to be suitable for structured illumination microscopy and two-photon microscopy (TPM). Results of TPM and confocal luminescence microscopy ensure lysosome specificity in live cells and tissue-dependent localization in zebrafish, respectively, of GQDs.

Graphical abstract: Two photon excitable graphene quantum dots for structured illumination microscopy and imaging applications: lysosome specificity and tissue-dependent imaging

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Article information

DOI
https://doi.org/10.1039/C8CC08610A
Article type
Communication
Submitted
28 Oct 2018
Accepted
28 Nov 2018
First published
29 Nov 2018

Chem. Commun., 2019,55, 521-524

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Two photon excitable graphene quantum dots for structured illumination microscopy and imaging applications: lysosome specificity and tissue-dependent imaging

H. Singh, S. Sreedharan, K. Tiwari, N. H. Green, C. Smythe, S. K. Pramanik, J. A. Thomas and A. Das, Chem. Commun., 2019, 55, 521 DOI: 10.1039/C8CC08610A

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