Issue 8, 2019
From the journal:

Chemical Communications

A smart perylene derived photosensitizer for lysosome-targeted and self-assessed photodynamic therapy†

Niu Niu,ab   Huipeng Zhou,a   Ning Liu,a   Hong Jiang,a   Ejaz Hussain,a   Zhenzhen Hua  and  Cong Yu ORCID logo *ab  

* Corresponding authors

a State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China
E-mail: congyu@ciac.ac.cn

b University of Science and Technology of China, Hefei, China

Abstract

A perylene probe PC4 is explored as a smart lysosome-targeted photosensitizer. It can efficiently kill cancer cells and also mark dead cells with bright fluorescence emission in nuclei for real-time monitoring and assessing of the photodynamic therapeutic efficiency.

Graphical abstract: A smart perylene derived photosensitizer for lysosome-targeted and self-assessed photodynamic therapy

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Article information

DOI
https://doi.org/10.1039/C8CC09396B
Article type
Communication
Submitted
26 Nov 2018
Accepted
20 Dec 2018
First published
21 Dec 2018

Chem. Commun., 2019,55, 1036-1039

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A smart perylene derived photosensitizer for lysosome-targeted and self-assessed photodynamic therapy

N. Niu, H. Zhou, N. Liu, H. Jiang, E. Hussain, Z. Hu and C. Yu, Chem. Commun., 2019, 55, 1036 DOI: 10.1039/C8CC09396B

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