Issue 47, 2018, Issue in Progress

Development and validation of a dispersive liquid–liquid microextraction method for the determination of phthalate esters in perfumes using gas chromatography-mass spectrometry

Abstract

A simple, rapid, sensitive and eco-friendly method has been developed for the simultaneous determination, preconcentration and extraction of phthalate esters (dimethyl phthalate, diethyl phthalate, dibutyl phthalate, benzyl butyl phthalate and bis(2-ethylhexyl) phthalate) in perfumes using dispersive liquid–liquid microextraction (DLLME) coupled to gas chromatography-mass spectrometry (GC-MS). Various factors affecting the DLLME efficiency, including the type and volume of the extracting and dispersing solvents, salt addition and vortex extraction time were optimized. Under optimum conditions, the proposed method provided low detection limits (0.003–0.070 ng mL−1), high extraction recovery (85.6–95.8%), wide linearity range (1.0–1000 ng mL−1) with good regression coefficients (>0.9984) and good precision (RSD% < 4.2%). The optimized method was successfully utilized for the analysis of different branded perfume samples and satisfactory results were obtained.

Graphical abstract: Development and validation of a dispersive liquid–liquid microextraction method for the determination of phthalate esters in perfumes using gas chromatography-mass spectrometry

Article information

Article type
Paper
Submitted
23 Apr 2018
Accepted
19 Jul 2018
First published
30 Jul 2018
This article is Open Access
Creative Commons BY license

RSC Adv., 2018,8, 26897-26905

Development and validation of a dispersive liquid–liquid microextraction method for the determination of phthalate esters in perfumes using gas chromatography-mass spectrometry

A. Mostafa and H. Shaaban, RSC Adv., 2018, 8, 26897 DOI: 10.1039/C8RA03488E

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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