Issue 100, 2019

Light-controlled out-of-equilibrium assembly of cyclodextrins in an enzyme-mediated dynamic system

Abstract

We show that the selective enzymatic synthesis of specific cyclodextrins can be modulated using light. We use enzyme-mediated dynamic combinatorial chemistry to generate a mixture of interconverting linear and cyclic α-1,4-glucans, and employ an azobenzene photoswitch as a template. Using UV or blue light to switch between photostationary states with different azobenzene cis/trans isomeric ratios, we can promote the out-of-equilibrium assembly of either α-cyclodextrin or β-cyclodextrin.

Graphical abstract: Light-controlled out-of-equilibrium assembly of cyclodextrins in an enzyme-mediated dynamic system

Supplementary files

Article information

Article type
Communication
Submitted
30 Oct 2019
Accepted
22 Nov 2019
First published
29 Nov 2019

Chem. Commun., 2019,55, 15037-15040

Light-controlled out-of-equilibrium assembly of cyclodextrins in an enzyme-mediated dynamic system

D. Larsen, P. M. Bjerre and S. R. Beeren, Chem. Commun., 2019, 55, 15037 DOI: 10.1039/C9CC08452E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements