Issue 18, 1996
From the journal:

Chemical Communications

Ferrous ion induced cleavage of the peroxy bond in qinghaosu and its derivatives and the DNA damage associated with this process

Wen-Min Wu,   Zhu-Jun Yao,   Yu-Lin Wu,   Kun Jiang,   Yan-Fang Wang,   Hai-Bao Cehn,   Feng Shan  and  Ying Li  

Abstract

In the presence of iron(II) the peroxy bridge of the drug quinghaosu and its derivatives and cleaved to give two rearrangement products; DNA damage due to this free radical process is observed an may be responsible for the antimalarial activity of these compounds.

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Article information

DOI
https://doi.org/10.1039/CC9960002213
Article type
Paper

Chem. Commun., 1996, 2213-2214

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Ferrous ion induced cleavage of the peroxy bond in qinghaosu and its derivatives and the DNA damage associated with this process

W. Wu, Z. Yao, Y. Wu, K. Jiang, Y. Wang, H. Cehn, F. Shan and Y. Li, Chem. Commun., 1996, 2213 DOI: 10.1039/CC9960002213

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