Issue 44, 2021
From the journal:

Chemical Communications

An enzyme nanopocket based on covalent organic frameworks for long-term starvation therapy and enhanced photodynamic therapy of cancer†

Xiuyan Wan,‡a   Huiwen Zhang,‡a   Wei Pan, ORCID logo a   Na Li ORCID logo *a  and  Bo Tang ORCID logo *a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Institute of Molecular and Nano Science, Shandong Normal University, Jinan 250014, P. R. China
E-mail: lina@sdnu.edu.cn, tangb@sdnu.edu.cn

Abstract

An enzyme nanopocket constructed from a porphyrin-based covalent organic framework (COF) was developed to co-load glucose oxidase (GOx) and catalase (CAT) for long-term starvation therapy and enhanced photodynamic therapy (PDT).

Graphical abstract: An enzyme nanopocket based on covalent organic frameworks for long-term starvation therapy and enhanced photodynamic therapy of cancer

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Article information

DOI
https://doi.org/10.1039/D0CC07544B
Article type
Communication
Submitted
17 Nov 2020
Accepted
22 Apr 2021
First published
23 Apr 2021

Chem. Commun., 2021,57, 5402-5405

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An enzyme nanopocket based on covalent organic frameworks for long-term starvation therapy and enhanced photodynamic therapy of cancer

X. Wan, H. Zhang, W. Pan, N. Li and B. Tang, Chem. Commun., 2021, 57, 5402 DOI: 10.1039/D0CC07544B

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