Issue 23, 2021

Recent advances in nanomaterial-based augmented sonodynamic therapy of cancer

Abstract

With interest in non-invasiveness and safety in cancer treatment, sonodynamic therapy (SDT) has emerged as a promising alternative to conventional cancer therapies. SDT offers safety and cost-effectiveness and exhibits a broad application range that is superior to photodynamic therapy. However, the insufficient reactive oxygen species (ROS) production of current sonosensitizers has hindered its clinical application to date. In this review, the ROS-generation mechanism in SDT and the limitations of current sonosensitizers are briefly reviewed. Also, highlighted are recent nanomaterial-based SDT strategies to improve the efficiency of sonosensitizers, amplify oxidative stress, and elicit antitumor immunity.

Graphical abstract: Recent advances in nanomaterial-based augmented sonodynamic therapy of cancer

Article information

Article type
Feature Article
Submitted
26 Nov 2020
Accepted
31 Jan 2021
First published
24 Feb 2021

Chem. Commun., 2021,57, 2854-2866

Recent advances in nanomaterial-based augmented sonodynamic therapy of cancer

W. Um, P. K. E. K., J. Lee, C. H. Kim, D. G. You and J. H. Park, Chem. Commun., 2021, 57, 2854 DOI: 10.1039/D0CC07750J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements