Issue 15, 2022
From the journal:

RSC Advances

An anthracenecarboximide-guanidine fluorescent probe for selective detection of glyoxals under weak acidic conditions†

Junwei Chen,‡a   Yuna Lin,‡a   Wanjin Xing,a   Xingchen Zhang,a   Huan Xu,*a   Wei Wang ORCID logo *b  and  Kaiyan Lou ORCID logo *a  

* Corresponding authors

a State Key Laboratory of Bioreactor Engineering, Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Shanghai Key Laboratory of New Drug Design, Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science & Technology, 130 Meilong Road, Shanghai 200237, China
E-mail: xuhuan@ecust.edu.cn, kylou@ecust.edu.cn

b A Department of Pharmacology and Toxicology and BIO5 Institute, University of Arizona, Tucson, AZ 85721-0207, USA
E-mail: wwang@pharmacy.arizona.edu

Abstract

An anthracenecarboximide-guanidine based turn-on fluorescent probe ANC-DCP-1 for selective detection of glyoxals (methylglyoxal and glyoxal, GOS) over formaldehyde under weak acidic conditions around pH 6.0 was reported. The probe showed great potential in studying relative GOS levels in weak acidic biological fluids such as in urine for diabetic diagnosis and prognosis, and also found application in the food industry such as for fast unique manuka factor (UMF) scale determination of Manuka honey.

Graphical abstract: An anthracenecarboximide-guanidine fluorescent probe for selective detection of glyoxals under weak acidic conditions

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Article information

DOI
https://doi.org/10.1039/D2RA00741J
Article type
Paper
Submitted
03 Feb 2022
Accepted
19 Mar 2022
First published
25 Mar 2022
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2022,12, 9473-9477

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An anthracenecarboximide-guanidine fluorescent probe for selective detection of glyoxals under weak acidic conditions

J. Chen, Y. Lin, W. Xing, X. Zhang, H. Xu, W. Wang and K. Lou, RSC Adv., 2022, 12, 9473 DOI: 10.1039/D2RA00741J

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