A visible-light-induced bromine radical initiates direct C–H alkylation of heteroaromatics

Abstract

Herein, a photoinduced direct C(sp²)–H alkylation of N-heteroaromatics by using commercially available tetrabutylammonium tribromide (TBATB) as a HAT reagent is described. The method uses O₂ as the oxidant, and features metal-free, mild reaction conditions and good functional group compatibility.