Intralayer hydrogen-bond-directed self-assembly of nano-fibers from dicarboxylic valylvaline bolaamphiphiles

Abstract

Dicarboxylic L-valyl-L-valine bolaamphiphiles produced nanoscale fibers with widths of 10–30 nm, via proton-triggered self-assembly in water, which are dominated by both intralayer, lateral hydrogen-bond networks between end carboxylic acid groups and parallel β-sheet networks between amide groups.