A Convenient Synthesis of (±)-3-Methoxybenzodioxane-4,9,9′-triol Neolignan, and Methyl Ethers of Isoamericanol A and Isoamericanin A
Abstract
The (±)-3-methoxybenzodioxane-4,9,9′-triol neolignan 9, and methyl ethers of isoamericanol A 8 and isoamericanin A 7 were synthesized from the readily available materials caffeic acid and ferulic acid, using a coupling reaction as a key step.