Issue 6, 2002

Modular fluorescence sensors for saccharides

Abstract

Modular photoinduced electron transfer (PET) sensors bearing two phenylboronic acid groups, a pyrene group and alkylene linkers, from trimethylene to octamethylene, have been prepared and evaluated. The diboronic acid systems with tetramethylene 3444 pentamethylene 3555 and hexamethylene 3666 linkers display the greatest enhancement in binding relative to monoboronic acid 4 with D-glucose. The diboronic acid system with the hexamethylene 3666 linker is particularly D-glucose selective and sensitive. Whilst the diboronic acid systems with the longer heptamethylene 3777 and octamethylene 3888 linkers display the greatest enhancement in binding relative to monoboronic acid 4 with D-galactose. All saccharide titrations were performed in methanolic aqueous solution.

Graphical abstract: Modular fluorescence sensors for saccharides

Article information

Article type
Paper
Submitted
05 Oct 2001
Accepted
22 Jan 2002
First published
15 Feb 2002

J. Chem. Soc., Perkin Trans. 1, 2002, 803-808

Modular fluorescence sensors for saccharides

S. Arimori, M. L. Bell, C. S. Oh, K. A. Frimat and T. D. James, J. Chem. Soc., Perkin Trans. 1, 2002, 803 DOI: 10.1039/B108998F

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