Ligand-free Pd/C-catalyzed Suzuki–Miyaura coupling reaction for the synthesis of heterobiaryl derivatives

Abstract

We have developed a mild and efficient protocol for the ligand-free and heterogeneous Pd/C-catalyzed hetero Suzuki–Miyaura coupling reaction that allows for the synthesis of both heteroaryl–aryl and heteroaryl–heteroaryl derivatives in good to excellent yields.