Issue 4, 2008

Glass coating for PDMS microfluidic channels by sol–gel methods

Abstract

Soft lithography using polydimethylsiloxane (PDMS) allows one to fabricate complex microfluidic devices easily and at low cost. However, PDMS swells in the presence of many organic solvents significantly degrading the performance of the device. We present a method to coat PDMS channels with a glass-like layer using sol–gel chemistry. This coating greatly increases chemical resistance of the channels; moreover, it can be functionalized with a wide range of chemicals to precisely control interfacial properties. This method combines the ease of fabrication afforded by soft-lithography with the precision control and chemical robustness afforded by glass.

Graphical abstract: Glass coating for PDMS microfluidic channels by sol–gel methods

Supplementary files

Article information

Article type
Communication
Submitted
03 Jan 2008
Accepted
12 Feb 2008
First published
20 Feb 2008

Lab Chip, 2008,8, 516-518

Glass coating for PDMS microfluidic channels by sol–gel methods

A. R. Abate, D. Lee, T. Do, C. Holtze and D. A. Weitz, Lab Chip, 2008, 8, 516 DOI: 10.1039/B800001H

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