Issue 32, 2008
From the journal:

Chemical Communications

Surface immobilization of biomolecules by click sulfonamide reaction†

Thimmaiah Govindaraju,ac   Pascal Jonkheijm,ac   Lars Gogolin,b   Hendrik Schroeder,d   Christian F. W. Becker,be   Christof M. Niemeyerd  and  Herbert Waldmann*ac  

* Corresponding authors

a Department of Chemical Biology, Max-Planck-Institut für Molekulare Physiologie, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany
E-mail: herbert.waldmann@mpi-dortmund.mpg.de
Fax: (+49) 231-133-2499

b Department of Physical Biochemistry, Max-Planck-Institut für Molekulare Physiologie, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany

c Chemische Biologie, Fachbereich Chemie, Technische Universität Dortmund, 44227 Dortmund, Germany

d Biologisch-Chemische Mikrostrukturtechnik, Fachbereich Chemie, Technische Universität Dortmund, 44227 Dortmund, Germany

e Technische Universität München and Center of Integrated Protein Science Munich (CIPSM), Fakultät Chemie, 85747 Garching, Germany

Abstract

Alkyne-modified biomolecules can be immobilized site- and chemoselectively on sulfonylazide slides under very mild conditions by means of the click sulfonamide reaction.

Graphical abstract: Surface immobilization of biomolecules by click sulfonamide reaction

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Article information

DOI
https://doi.org/10.1039/B806764C
Article type
Communication
Submitted
21 Apr 2008
Accepted
25 Jun 2008
First published
15 Jul 2008

Chem. Commun., 2008, 3723-3725

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Surface immobilization of biomolecules by click sulfonamide reaction

T. Govindaraju, P. Jonkheijm, L. Gogolin, H. Schroeder, C. F. W. Becker, C. M. Niemeyer and H. Waldmann, Chem. Commun., 2008, 3723 DOI: 10.1039/B806764C

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