Issue 10, 2008

An active bubble trap and debubbler for microfluidic systems

Abstract

We present a novel, fully integrated microfluidic bubble trap and debubbler. The 2-layer structure, based on a PDMS valve design, utilizes a featured membrane to stop bubble progression through the device. A pneumatic chamber directly above the trap is evacuated, and the bubble is pulled out through the gas-permeable PDMS membrane. Normal device operation, including continuous flow at atmospheric pressure, is maintained during the entire trapping and debubbling process. We present a range of trap sizes, from 2 to 10 mm diameter, and can trap and remove bubbles up to 25 μL in under 3 h.

Graphical abstract: An active bubble trap and debubbler for microfluidic systems

Supplementary files

Article information

Article type
Technical Note
Submitted
29 Apr 2008
Accepted
16 Jul 2008
First published
28 Aug 2008

Lab Chip, 2008,8, 1733-1737

An active bubble trap and debubbler for microfluidic systems

A. M. Skelley and J. Voldman, Lab Chip, 2008, 8, 1733 DOI: 10.1039/B807037G

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