Issue 26, 2008
From the journal:

Chemical Communications

Exploiting domino enyne metathesismechanisms for skeletal diversity generation†‡

Richard J. Spandl,a   Hèléne Rudykb  and  David R. Spring*a  

* Corresponding authors

a Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK
E-mail: drspring@ch.cam.ac.uk
Tel: +44 (0)1223 336498

b Lilly UK, Erl Wood Manor, Windlesham, Surrey, UK

Abstract

In the context of diversity-oriented synthesis, the exploration and optimization of the domino metathesis of decorated norbornenes allowed complex polycyclic architectures to be generated in a highly efficient and atom-economical process.

Graphical abstract: Exploiting domino enyne metathesismechanisms for skeletal diversity generation

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Article information

DOI
https://doi.org/10.1039/B807278G
Article type
Communication
Submitted
29 Apr 2008
Accepted
09 May 2008
First published
03 Jun 2008

Chem. Commun., 2008, 3001-3003

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Exploiting domino enyne metathesismechanisms for skeletal diversity generation

R. J. Spandl, H. Rudyk and D. R. Spring, Chem. Commun., 2008, 3001 DOI: 10.1039/B807278G

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