Issue 40, 2008

Efficient copper-free Sonogashira coupling of aryl chlorides with palladium on charcoal

Abstract

Palladium on charcoal serves as an efficient and reusable solid supported catalyst for the Sonogashira coupling of aryl chlorides with terminal acetylenes in the presence of a bulky, electron-rich biphenyl type ligand (XPhos), without copper co-catalyst.

Graphical abstract: Efficient copper-free Sonogashira coupling of aryl chlorides with palladium on charcoal

Supplementary files

Article information

Article type
Communication
Submitted
27 Jun 2008
Accepted
11 Jul 2008
First published
08 Sep 2008

Chem. Commun., 2008, 4968-4970

Efficient copper-free Sonogashira coupling of aryl chlorides with palladium on charcoal

A. Komáromi and Z. Novák, Chem. Commun., 2008, 4968 DOI: 10.1039/B810928A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements