Issue 41, 2008
From the journal:

Chemical Communications

Photoactivatable HNO-releasing compounds using the retro-Diels–Alder reaction†

Yusuke Adachi,a   Hidehiko Nakagawa,*a   Kazuya Matsuo,a   Takayoshi Suzukia  and  Naoki Miyata*a  

* Corresponding authors

a Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Japan
E-mail: deco@phar.nagoya-cu.ac.jp, miyata-n@phar.nagoya-cu.ac.jp
Fax: +81-52-836-3407
Tel: +81-52-836-3408

Abstract

We synthesized hetero-Diels–Alder cycloadducts from acyl nitroso derivatives and 9,10-dimethylanthracene, to be photo-inducible HNO-releasing agents and found that introduction of conjugated nitroaromatic groups effectively enhanced the responsiveness of HNO release to UV-A irradiation; we confirmed photoinduced HNO formation by EPR and GCMS analysis.

Graphical abstract: Photoactivatable HNO-releasing compounds using the retro-Diels–Alder reaction

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B811985F
Article type
Communication
Submitted
14 Jul 2008
Accepted
02 Sep 2008
First published
23 Sep 2008

Chem. Commun., 2008, 5149-5151

Permissions

Request permissions

Photoactivatable HNO-releasing compounds using the retro-Diels–Alder reaction

Y. Adachi, H. Nakagawa, K. Matsuo, T. Suzuki and N. Miyata, Chem. Commun., 2008, 5149 DOI: 10.1039/B811985F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements