Issue 12, 2009
From the journal:

Lab on a Chip

“Smart dust” biosensors powered by biomolecular motors

George D. Bachand,a   Henry Hess,*b   Banahalli Ratna,c   Peter Satird  and  Viola Vogele  

* Corresponding authors

a Center for Integrated Nanotechnologies, Sandia National Laboratories, Albuquerque, NM, USA

b Dept of Materials Science and Engineering, University of Florida, Gainesville, FL, USA
E-mail: hhess@mse.ufl.edu
Fax: (+1352) 846-3355
Tel: (+1352) 846-3781

c Center for Bio/Molecular Science and Engineering, Naval Research Laboratory, Washington, DC, USA

d Dept of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY, USA

e Laboratory of Biologically Oriented Materials, Department of Materials, ETH Zurich, CH, Switzerland

Abstract

The concept of a microfabricated biosensor for environmental and biomedical monitoring applications which is composed of environmentally benign components is presented. With a built-in power source (the biological fuel ATP) and driven by biological motors (kinesin), sensing in the microdevice can be remotely activated and the presence of a target molecule or toxin remotely detected. The multifaceted progress towards the realization of such a device is described.

Graphical abstract: “Smart dust” biosensors powered by biomolecular motors

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Article information

DOI
https://doi.org/10.1039/B821055A
Article type
Frontier
Submitted
27 Nov 2008
Accepted
02 Mar 2009
First published
18 Mar 2009

Lab Chip, 2009,9, 1661-1666

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“Smart dust” biosensors powered by biomolecular motors

G. D. Bachand, H. Hess, B. Ratna, P. Satir and V. Vogel, Lab Chip, 2009, 9, 1661 DOI: 10.1039/B821055A

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