Issue 21, 2009

Chemically-selective surface glyco-functionalization of liposomes through Staudinger ligation

Abstract

An efficient and chemoselective liposome surface glyco-functionalization method has been developed based on Staudinger ligation, in which the carbohydrate derivative carrying an azide spacer is conjugated onto the surface of preformed liposomes bearing a terminal triphosphine in PBSbuffer (pH 7.4) at room temperature.

Graphical abstract: Chemically-selective surface glyco-functionalization of liposomes through Staudinger ligation

Supplementary files

Article information

Article type
Communication
Submitted
15 Dec 2008
Accepted
19 Mar 2009
First published
28 Apr 2009

Chem. Commun., 2009, 3032-3034

Chemically-selective surface glyco-functionalization of liposomes through Staudinger ligation

H. Zhang, Y. Ma and X. Sun, Chem. Commun., 2009, 3032 DOI: 10.1039/B822420J

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