Issue 14, 2009

Polycyclic alkaloidsvia transannular Mannich reactions

Abstract

The tricyclic compound 13, representing the framework of the cylindricine 4 and lepadiformine 5alkaloids, was prepared in a single operation via the first example of a transannular Mannich reaction involving a macrocyclic diketoamine 12.

Graphical abstract: Polycyclic alkaloidsvia transannular Mannich reactions

Supplementary files

Article information

Article type
Communication
Submitted
19 Dec 2008
Accepted
28 Jan 2009
First published
19 Feb 2009

Chem. Commun., 2009, 1888-1890

Polycyclic alkaloidsvia transannular Mannich reactions

P. Vital, M. Hosseini, M. S. Shanmugham, C. H. Gotfredsen, P. Harris and D. Tanner, Chem. Commun., 2009, 1888 DOI: 10.1039/B822955D

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