Issue 19, 2009

Chemo-/regioselective synthesis of 6-unsubstituted dihydropyrimidinones, 1,3-thiazines and chromonesvia novel variants of Biginelli reaction

Abstract

A novel and facile cascade Biginelli-like assembly employing enaminone, aldehyde and urea/thiourea has been developed, which provides a highly chemo- and regioselective synthesis of new dihydropyrimidinones, 1,3-thiazines and chromones by altering particular functional groups in the reactants.

Graphical abstract: Chemo-/regioselective synthesis of 6-unsubstituted dihydropyrimidinones, 1,3-thiazines and chromonesvia novel variants of Biginelli reaction

Supplementary files

Article information

Article type
Communication
Submitted
19 Jan 2009
Accepted
10 Mar 2009
First published
30 Mar 2009

Chem. Commun., 2009, 2768-2770

Chemo-/regioselective synthesis of 6-unsubstituted dihydropyrimidinones, 1,3-thiazines and chromonesvia novel variants of Biginelli reaction

J. Wan and Y. Pan, Chem. Commun., 2009, 2768 DOI: 10.1039/B901112A

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