Issue 8, 2009

Mirror image phage display—a method to generate d-peptideligands for use in diagnostic or therapeutical applications

Abstract

Mirror image phage display is a straightforward approach to identify new potentially therapeutically active D-enantiomeric peptides. Such D-peptides are more resistant to proteolytic degradation compared to L-peptides. In this review, several examples of mirror image phage display derived D-peptides with therapeutical potential are introduced and discussed.

Graphical abstract: Mirror image phage display—a method to generate d-peptideligands for use in diagnostic or therapeutical applications

Article information

Article type
Review Article
Submitted
27 Feb 2009
Accepted
30 Apr 2009
First published
12 Jun 2009

Mol. BioSyst., 2009,5, 783-786

Mirror image phage display—a method to generate D-peptideligands for use in diagnostic or therapeutical applications

S. A. Funke and D. Willbold, Mol. BioSyst., 2009, 5, 783 DOI: 10.1039/B904138A

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