Issue 43, 2009
From the journal:

Chemical Communications

DNA templated nucleophilicaromatic substitution reactions for fluorogenic sensing of oligonucleotides†

Aya Shibata,a   Hiroshi Abe,*a   Mika Ito,ab   Yuko Kondo,ac   Shigeru Shimizu,b   Kyoko Aikawac  and  Yoshihiro Ito*a  

* Corresponding authors

a Nano Medical Engineering Laboratory, RIKEN Advanced Science Institute, 2-1, Hirosawa, Wako-Shi, Saitama 351-0198, Japan
E-mail: h-abe@riken.jp; y-ito@riken.jp

b Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, 1-8-14, Kanda-Surugadai, Chiyoda-ku, Tokyo 101-8308, Japan

c Department of Chemistry, Faculty of Science, Ochanomizu University, 2-1-1 Otsuka, Bunkyo-ku, Tokyo 112-8610, Japan

Abstract

We have developed an SNAr reaction-triggered fluorescence probe using a new fluorogenic compound derivatized from 7-aminocoumarin for oligonucleotides detection.

Graphical abstract: DNA templated nucleophilicaromatic substitution reactions for fluorogenic sensing of oligonucleotides

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Article information

DOI
https://doi.org/10.1039/B912896D
Article type
Communication
Submitted
30 Jun 2009
Accepted
23 Sep 2009
First published
05 Oct 2009

Chem. Commun., 2009, 6586-6588

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DNA templated nucleophilicaromatic substitution reactions for fluorogenic sensing of oligonucleotides

A. Shibata, H. Abe, M. Ito, Y. Kondo, S. Shimizu, K. Aikawa and Y. Ito, Chem. Commun., 2009, 6586 DOI: 10.1039/B912896D

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