Issue 38, 2009

β-Amidoaldehydes viaoxazolinehydroformylation

Abstract

4-Substituted oxazolines, which are readily synthesized from naturally occurring α-amino acids, are converted efficiently and stereospecifically to β-amidoaldehydes in the presence of synthesis gas and catalytic dicobalt octacarbonyl.

Graphical abstract: β-Amidoaldehydes viaoxazolinehydroformylation

Supplementary files

Article information

Article type
Communication
Submitted
09 Jul 2009
Accepted
10 Aug 2009
First published
01 Sep 2009

Chem. Commun., 2009, 5704-5706

β-Amidoaldehydes viaoxazolinehydroformylation

D. S. Laitar, J. W. Kramer, B. T. Whiting, E. B. Lobkovsky and G. W. Coates, Chem. Commun., 2009, 5704 DOI: 10.1039/B913698C

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