Issue 21, 2010
From the journal:

Chemical Communications

A unique proteinlabeling system based on melittin and the non-covalent binding-induced pyrene excimer†

Yue Li,a   Hong-Wei Li,a   Li-Jun Ma,a   Yong-Qiang Danga  and  Yuqing Wu*a  

* Corresponding authors

a State Key Laboratory of Supramolecular Structure and Materials, Jilin University, No. 2699, Qianjin Street, Changchun, China
E-mail: yqwu@jlu.edu.cn
Fax: +86-431-85193421
Tel: +86-431-85168730

Abstract

We report a unique protein labeling system based on melittin and a pyrene derivative (1). The specific region of the C-terminal in melittin efficiently induced the formation of the pyrene eximer, which can be used as a tag to target proteins and for further detection.

Graphical abstract: A unique protein labeling system based on melittin and the non-covalent binding-induced pyrene excimer

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Article information

DOI
https://doi.org/10.1039/B925401C
Article type
Communication
Submitted
02 Dec 2009
Accepted
01 Apr 2010
First published
22 Apr 2010

Chem. Commun., 2010,46, 3768-3770

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A unique protein labeling system based on melittin and the non-covalent binding-induced pyrene excimer

Y. Li, H. Li, L. Ma, Y. Dang and Y. Wu, Chem. Commun., 2010, 46, 3768 DOI: 10.1039/B925401C

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