Issue 32, 2010

First sequential Mukaiyama–Michael reaction/crossed-Claisen condensation using two molar ketene silyl acetals and one molar α,β-unsaturated esters promoted by a NaOHcatalyst

Abstract

The NaOH-catalyzed first sequential Mukaiyama–Michael reaction/crossed-Claisen condensation is developed using two molar ketene silyl acetals and one molar α,β-unsaturated esters in either a stepwise or one-pot manner.

Graphical abstract: First sequential Mukaiyama–Michael reaction/crossed-Claisen condensation using two molar ketene silyl acetals and one molar α,β-unsaturated esters promoted by a NaOH catalyst

Supplementary files

Article information

Article type
Communication
Submitted
25 Apr 2010
Accepted
09 Jun 2010
First published
02 Jul 2010

Chem. Commun., 2010,46, 5930-5932

First sequential Mukaiyama–Michael reaction/crossed-Claisen condensation using two molar ketene silyl acetals and one molar α,β-unsaturated esters promoted by a NaOH catalyst

H. Tamagaki, Y. Nawate, R. Nagase and Y. Tanabe, Chem. Commun., 2010, 46, 5930 DOI: 10.1039/C0CC01110J

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