Issue 37, 2010

First synthesis of 3-aryl-4-unsubstituted-6-CF3-pyridin-2-ones via aryl migration reaction in the presence of PhI(OAc)2/NaOH

Abstract

3-Aryl-4-unsubstituted-6-CF3-pyridin-2-ones have been efficiently synthesized from readily available 4-aryl-3-carbamoyl-6-CF3-pyridin-2(1H)-ones by treatment with PhI(OAc)2 in the presence of NaOH.

Graphical abstract: First synthesis of 3-aryl-4-unsubstituted-6-CF3-pyridin-2-ones via aryl migration reaction in the presence of PhI(OAc)2/NaOH

Supplementary files

Article information

Article type
Communication
Submitted
10 Jun 2010
Accepted
22 Jul 2010
First published
23 Aug 2010

Chem. Commun., 2010,46, 6941-6943

First synthesis of 3-aryl-4-unsubstituted-6-CF3-pyridin-2-ones via aryl migration reaction in the presence of PhI(OAc)2/NaOH

H. Yi, L. Song, W. Wang, J. Liu, S. Zhu, H. Deng and M. Shao, Chem. Commun., 2010, 46, 6941 DOI: 10.1039/C0CC01815E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements