Issue 21, 2011

Cholinedendrimers as generic scaffolds for the non-covalent synthesis of multivalent proteinassemblies

Abstract

A modular self-assembly strategy is presented that allows the non-covalent synthesis of multivalent protein dendrimers using the strong interaction between choline-functionalized dendrimers and the choline binding protein C-LytA. Choline dendrimers displaying fusion proteins of C-LytA and the collagen binding protein CNA35 represent attractive multivalent targeting ligands for collagen imaging.

Graphical abstract: Choline dendrimers as generic scaffolds for the non-covalent synthesis of multivalent protein assemblies

Supplementary files

Article information

Article type
Communication
Submitted
15 Dec 2010
Accepted
05 Apr 2011
First published
21 Apr 2011

Chem. Commun., 2011,47, 5997-5999

Choline dendrimers as generic scaffolds for the non-covalent synthesis of multivalent protein assemblies

V. M. Hernández-Rocamora, S. W. A. Reulen, B. de Waal, E. W. Meijer, J. M. Sanz and M. Merkx, Chem. Commun., 2011, 47, 5997 DOI: 10.1039/C0CC05605G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements