Issue 30, 2011

Design of a reversible biotin analog and applications in proteinlabeling, detection, and isolation

Abstract

To expand the applicability of the biotin–(strept)avidin system, a biotin analog with reversible binding under non-denaturing conditions has been designed, and its applications in protein labeling, detection, and isolation have been evaluated.

Graphical abstract: Design of a reversible biotin analog and applications in protein labeling, detection, and isolation

Supplementary files

Article information

Article type
Communication
Submitted
10 May 2011
Accepted
10 Jun 2011
First published
27 Jun 2011

Chem. Commun., 2011,47, 8593-8595

Design of a reversible biotin analog and applications in protein labeling, detection, and isolation

L. Ying and B. P. Branchaud, Chem. Commun., 2011, 47, 8593 DOI: 10.1039/C1CC12738A

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