Issue 5, 2011
From the journal:

RSC Advances

Patterning cell using Si-stencil for high-throughput assay

Jinbo Wu,a   Mengying Zhang,a   Longqing Chen,b   Vivian Yu,c   Joseph Tin-Yum Wong,c   Xixiang Zhang,b   Jianhua Qind  and  Weijia Wen*a  

* Corresponding authors

a The Department of Physics and KAUST-HKUST Micro/Nanofluidic Joint Laboratory, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong
E-mail: phwen@ust.hk
Fax: 852 23581652
Tel: 852 23587979

b Advanced Nanofabrication, Imaging and Characterization Core Lab, King Abdullah University of Science and Technology, Thuwal 23955-6900, Kingdom of Saudi Arabia

c Division of Life Science, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong

d Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457, Zhongshan Road, 11603, China

Abstract

In this communication, we report a newly developed cell pattering methodology by a silicon-based stencil, which exhibited advantages such as easy handling, reusability, hydrophilic surface and mature fabrication technologies. Cell arrays obtained by this method were used to investigate cell growth under a temperature gradient, which demonstrated the possibility of studying cell behavior in a high-throughput assay.

Graphical abstract: Patterning cell using Si-stencil for high-throughput assay

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Article information

DOI
https://doi.org/10.1039/C1RA00520K
Article type
Communication
Submitted
27 Jul 2011
Accepted
29 Jul 2011
First published
31 Aug 2011

RSC Adv., 2011,1, 746-750

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Patterning cell using Si-stencil for high-throughput assay

J. Wu, M. Zhang, L. Chen, V. Yu, J. Tin-Yum Wong, X. Zhang, J. Qin and W. Wen, RSC Adv., 2011, 1, 746 DOI: 10.1039/C1RA00520K

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