Highly sensitive turn-on detection of Ag+ in aqueous solution and live cells with a symmetric fluorescent peptide

Joung-Min Kim; Chuda Raj Lohani; Lok Nath Neupane; Youngsik Choi; Keun-Hyeung Lee

doi:10.1039/C2CC16953C

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Highly sensitive turn-on detection of Ag⁺ in aqueous solution and live cells with a symmetric fluorescent peptide†

Joung-Min Kim,^a Chuda Raj Lohani,^a Lok Nath Neupane,^a Youngsik Choi^a and Keun-Hyeung Lee*^a

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* Corresponding authors

^a Department of Chemistry, Bioorganic Chemistry Lab, Inha University, 253 Yunghyun-dong, Nam-Gu, Incheon city, South Korea
E-mail: leekh@inha.ac.kr
Fax: +82-32-8675604
Tel: +82-32-8607674

Abstract

This communication presents a symmetric fluorescent peptide (K_d = 17.4 nM) for hypersensitively detecting Ag⁺ in 100% aqueous solution by turn-on response. The peptide penetrated live HeLa cells and detected intracellular Ag⁺ by turn-on response.

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Article information

DOI: https://doi.org/10.1039/C2CC16953C
Article type: Communication
Submitted: 09 Nov 2011
Accepted: 17 Jan 2012
First published: 10 Feb 2012

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Chem. Commun., 2012,48, 3012-3014

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Highly sensitive turn-on detection of Ag⁺ in aqueous solution and live cells with a symmetric fluorescent peptide

J. Kim, C. R. Lohani, L. N. Neupane, Y. Choi and K. Lee, Chem. Commun., 2012, 48, 3012 DOI: 10.1039/C2CC16953C

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