Gd(III)-doped carbon dots as a dual fluorescent-MRI probe

Athanasios B. Bourlinos; Aristides Bakandritsos; Antonios Kouloumpis; Dimitrios Gournis; Marta Krysmann; Emmanuel P. Giannelis; Katerina Polakova; Klara Safarova; Katerina Hola; Radek Zboril

doi:10.1039/C2JM35592B

Gd(iii)-doped carbon dots as a dual fluorescent-MRI probe†

Athanasios B. Bourlinos,^a Aristides Bakandritsos,^b Antonios Kouloumpis,^c Dimitrios Gournis,^c Marta Krysmann,^d Emmanuel P. Giannelis,*^de Katerina Polakova,^f Klara Safarova,^f Katerina Hola^f and Radek Zboril*^f

Author affiliations

* Corresponding authors

^a Physics Department, University of Ioannina, 45110 Ioannina, Greece

^b Department of Materials Science, University of Patras, 26504 Rio, Patras, Greece

^c Department of Materials Science and Engineering, University of Ioannina, 45110 Ioannina, Greece

^d Materials Science and Engineering, Cornell University, Ithaca, New York 14853, USA
E-mail: epg2@cornell.edu
Fax: +1 6072552365
Tel: +1 6072559680

^e Center for Refining and Petrochemicals, KFUPM, Dhahran-31261, Saudi Arabia

^f Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Faculty of Science, Palacky University, 17. listopadu 1192/12, 77146 Olomouc, Czech Republic
E-mail: zboril@prfnw.upol.cz
Fax: +420 585634761
Tel: +420 585634947

Abstract

We describe the synthesis of Gd(III)-doped carbon dots as dual fluorescence-MRI probes for biomedical applications. The derived Gd(III)-doped carbon dots show uniform particle size (3–4 nm) and gadolinium distribution and form stable dispersions in water. More importantly, they exhibit bright fluorescence, strong T1-weighted MRI contrast and low cytotoxicity.

Journal of Materials Chemistry

Gd(iii)-doped carbon dots as a dual fluorescent-MRI probe†

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Gd(III)-doped carbon dots as a dual fluorescent-MRI probe

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