Issue 11, 2012

Carbazole–thiosemicarbazone–Hg(ii) ensemble-based colorimetric and fluorescence turn-on toward iodide in aqueous media and its application in live cell imaging

Abstract

A carbazole–thiosemicarbazone–Hg2+ ensemble-based fluorogenic probe for detection of iodide in aqueous media is reported. The first fluorescent sensor for iodide anions was constructed based on the displacement approach. An ‘ensemble’ is able to selectively sense iodide over other anions followed by the release of 9-(butane-1-yl)-9H-carbazole-3,6-dihydrazinecarbothioamide to give a remarkable change of fluorescence turn-on signal at pH 7.4 under aqueous media. The practical use of an ‘ensemble’ was demonstrated by its application to the detection of iodide in the living cells.

Graphical abstract: Carbazole–thiosemicarbazone–Hg(ii) ensemble-based colorimetric and fluorescence turn-on toward iodide in aqueous media and its application in live cell imaging

Supplementary files

Article information

Article type
Paper
Submitted
25 Oct 2011
Accepted
12 Dec 2011
First published
13 Dec 2011

Org. Biomol. Chem., 2012,10, 2231-2236

Carbazole–thiosemicarbazone–Hg(II) ensemble-based colorimetric and fluorescence turn-on toward iodide in aqueous media and its application in live cell imaging

A. K. Mahapatra, J. Roy, P. Sahoo, S. K. Mukhopadhyay and A. Chattopadhyay, Org. Biomol. Chem., 2012, 10, 2231 DOI: 10.1039/C2OB06792G

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