Issue 6, 2015

High resolution Raman spectroscopy mapping of stem cell micropatterns

Abstract

We report on the use of high resolution Raman spectroscopy mapping combined with a micro-engineered stem cell platform. This technique obtains quantitative information about the concentration of individual intracellular molecules such as proteins, lipids, and other metabolites, while tightly controlling cell shape and adhesion. This new quantitative analysis will prove highly relevant for in vitro drug screening applications and regenerative medicine.

Graphical abstract: High resolution Raman spectroscopy mapping of stem cell micropatterns

Supplementary files

Article information

Article type
Communication
Submitted
19 Dec 2014
Accepted
04 Feb 2015
First published
11 Feb 2015
This article is Open Access
Creative Commons BY license

Analyst, 2015,140, 1798-1803

Author version available

High resolution Raman spectroscopy mapping of stem cell micropatterns

T. C. von Erlach, M. A. B. Hedegaard and M. M. Stevens, Analyst, 2015, 140, 1798 DOI: 10.1039/C4AN02346C

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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