Evaluating the effects of nacre on human skin and scar cells in culture

Vipul Agarwal; Edwin S. Tjandra; K. Swaminathan Iyer; Barry Humfrey; Mark Fear; Fiona M. Wood; Sarah Dunlop; Colin L. Raston

doi:10.1039/C4TX00004H

Evaluating the effects of nacre on human skin and scar cells in culture†

Vipul Agarwal,^a Edwin S. Tjandra,^a K. Swaminathan Iyer,^a Barry Humfrey,^b Mark Fear,^c Fiona M. Wood,^c Sarah Dunlop^d and Colin L. Raston*^e

Author affiliations

* Corresponding authors

^a School of Chemistry and Biochemistry, The University of Western Australia, Crawley, Australia

^b Pearl Technology Pty Ltd, Geraldton, Australia

^c Burn Injury Research Unit, School of Surgery, The University of Western Australia, Crawley, Australia

^d School of Animal Biology, The University of Western Australia, Crawley, Australia

^e School of Chemical and Physical Sciences, Flinders University, Bedford Park, Australia
E-mail: colin.raston@flinders.edu.au
Tel: +61 82017958

Abstract

Pearl nacre, a biomineralisation product of molluscs, has growing applications in cosmetics, as well as dental and bone restoration, yet a systematic evaluation of its biosafety is lacking. Here, we assessed the biocompatibility of nacre with two human primary dermal fibroblast cell cultures and an immortalised epidermal cell line and found no adverse effects.

Toxicology Research

Evaluating the effects of nacre on human skin and scar cells in culture†

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