Issue 64, 2016, Issue in Progress
From the journal:

RSC Advances

New insights into an innovative Auricularia auricular polysaccharide pH-sensitive hydrogel for controlled protein drug delivery†

Yibin Yu,‡a   Hao Pan,‡b   Yingying Wang,a   Wei Xiong,a   Qiantao Zhang,c   Kai Chen,a   Xiumei Gai,a   Pingfei Lia  and  Xinggang Yang*ad  

* Corresponding authors

a Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China
E-mail: yangxg123@163.com
Fax: +86-24-23953241
Tel: +86-24-23986313

b School of Pharmacy, Queen's University Belfast, Belfast BT7 1NN, UK

c Shanxi Institute of International Trade & Commerce, Shanxi 712046, China

d State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Progress, Lianyungang 222001, China

Abstract

A novel hydrogel based on Auricularia auricular polysaccharide (AAP), was prepared and characterized. AAP hydrogel exhibited a pH-sensitive release of model protein drug (bovine serum albumin, BSA) under simulated gastrointestinal conditions. The results indicate AAP hydrogel has promising potential as an effective vehicle for oral delivery of protein.

Graphical abstract: New insights into an innovative Auricularia auricular polysaccharide pH-sensitive hydrogel for controlled protein drug delivery

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Article information

DOI
https://doi.org/10.1039/C6RA06463A
Article type
Communication
Submitted
10 Mar 2016
Accepted
10 Jun 2016
First published
16 Jun 2016

RSC Adv., 2016,6, 59794-59799

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New insights into an innovative Auricularia auricular polysaccharide pH-sensitive hydrogel for controlled protein drug delivery

Y. Yu, H. Pan, Y. Wang, W. Xiong, Q. Zhang, K. Chen, X. Gai, P. Li and X. Yang, RSC Adv., 2016, 6, 59794 DOI: 10.1039/C6RA06463A

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