Issue 19, 2017

A highly selective “ON–OFF” probe for colorimetric and fluorometric sensing of Cu2+ in water

Abstract

We present herein a diformyl phenol based probe, 3-({3-[2,3-dihydroxy-propylimino-methyl]-2-hydroxy-5-methyl-benzylidene}-amino)-propane-1,2-diol (H5dpm), as a colorimetric and fluorometric chemosensor for selective detection of Cu2+ in aqueous solution under physiological conditions. This simple system produces a colorimetric change enabling naked eye detection as well as on–off fluorescence response towards Cu2+ in an aqueous medium with a detection limit of 11.2 nM. To further demonstrate the utility of H5dpm, we next explored the application of H5dpm for imaging Cu2+ in Vero cells. The attractive imaging properties of the H5dpm probe will open up avenues for molecular imaging and biomedical applications.

Graphical abstract: A highly selective “ON–OFF” probe for colorimetric and fluorometric sensing of Cu2+ in water

Supplementary files

Article information

Article type
Paper
Submitted
18 Nov 2016
Accepted
07 Feb 2017
First published
13 Feb 2017
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2017,7, 11312-11321

A highly selective “ON–OFF” probe for colorimetric and fluorometric sensing of Cu2+ in water

B. Naskar, R. Modak, D. K. Maiti, A. Bauzá, A. Frontera, P. K. Maiti, S. Mandal and S. Goswami, RSC Adv., 2017, 7, 11312 DOI: 10.1039/C6RA27017D

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