Issue 29, 2017, Issue in Progress

Preparation of [18F]-NHC-BF3 conjugates and their applications in PET imaging

Abstract

N-Heterocyclic carbene boron trifluoride (NHC-BF3) conjugates were successfully radiofluorinated by SnCl4-promoted 18F–19F isotopic exchange reaction in one labelling step. This method afforded in vivo stable PET agents that efficiently bound to targeted tumours yielding PET images with good tumour-to-background contrast.

Graphical abstract: Preparation of [18F]-NHC-BF3 conjugates and their applications in PET imaging

Supplementary files

Article information

Article type
Paper
Submitted
29 Dec 2016
Accepted
14 Mar 2017
First published
22 Mar 2017
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2017,7, 17748-17751

Preparation of [18F]-NHC-BF3 conjugates and their applications in PET imaging

K. Chansaenpak, M. Wang, H. Wang, B. C. Giglio, F. P. Gabbaï, Z. Wu and Z. Li, RSC Adv., 2017, 7, 17748 DOI: 10.1039/C6RA28806E

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