Issue 2, 2017

Au(iii)-aryl intermediates in oxidant-free C–N and C–O cross-coupling catalysis

Abstract

Au(III)-aryl species have been unequivocally identified as reactive intermediates in oxidant-free C–O and C–N cross coupling catalysis. The crystal structures of cyclometalated neutral and cationic Au(III) species are described and their key role in 2 electron-redox Au(I)/Au(III) catalysis in C–O and C–N cross couplings is shown. Nucleophiles compatible with Au-catalyzed cross couplings include aromatic and aliphatic alcohols and amines, as well as water and amides.

Graphical abstract: Au(iii)-aryl intermediates in oxidant-free C–N and C–O cross-coupling catalysis

Supplementary files

Article information

Article type
Edge Article
Submitted
17 Aug 2016
Accepted
22 Sep 2016
First published
23 Sep 2016
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2017,8, 946-952

Au(III)-aryl intermediates in oxidant-free C–N and C–O cross-coupling catalysis

J. Serra, T. Parella and X. Ribas, Chem. Sci., 2017, 8, 946 DOI: 10.1039/C6SC03699F

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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